The latter, based on the memoir by Cheryl Strayed, stars Witherspoon as a woman who takes to the road after the death of her mother.
Witherspoon earned rave reviews for the role, receiving Oscar, Golden Globe and SAG award nominations. She also launched a Southern-inspired home and apparel line called Draper James that year.
She and Ryan Phillippe announced their separation in October 2006 and divorced the following year.
In an interview with Charlie Rose in 2014, Witherspoon opened up about the dissolution of their marriage. You know, you can't really be very creative when you feel like your brain is scrambled eggs," she told Rose.
The couple married in 1999, and welcomed two children soon after: daughter Ava Elizabeth (born in 1999) and son Deacon (2003)..The stars began dating shortly afterward, but their romance didn't last long; the Hollywood "It" couple split in 2009.